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E7766 diammonium salt

Product Specifications

CAS Number

2242635-03-4

Target

Others, STING

Related Pathways

Immunology/Inflammation, Others

Bioactivity

E7766 diammonium salt, a macrocycle-bridged STING agonist, exhibits a dissociation constant (Kd) of 40 nM, demonstrating potent pan-genotypic and antitumor activities.

Smiles

F[C@H]1[C@@]2(N3C4=C(N=C3)C(N=CN4)=NC/C=C/CNC=5C6=C(N([C@@]7(O[C@@]8(COP(=O)(S)O[C@@]1([C@](O2)(COP(=O)(S)O[C@]8([C@H]7F)[H])[H])[H])[H])[H])C=N6)N=CN5)[H].N

Molecular Formula

C24H32F2N12O8P2S2

Molecular Weight

780.66

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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