TTC-352
Product Specifications
CAS Number
1607819-68-0
Target
Estrogen Receptor/ERR|||Others
Related Pathways
Others|||Endocrinology/Hormones
Bioactivity
TTC-352 is an orally bioavailable selective human estrogen receptor alpha (ERalpha; ESR1; ERa) partial agonist (ShERPA), with potential antineoplastic activity. Upon administration, TTC-352 mimics the naturally-occurring 17beta-estradiol (E2) and targets and binds to ERa located in the nucleus. This causes translocation of ERa to extranuclear sites. Nuclear export of ERa prevents normal ER-mediated signaling and inhibits proliferation of ER-positive tumor cells.
Smiles
O(C1=C(C=2C(S1)=CC(O)=CC2)C3=CC=C(F)C=C3)C4=CC=C(O)C=C4
Molecular Formula
C20H13FO3S
Molecular Weight
352.38
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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