APBC
Product Specifications
CAS Number
324054-99-1
Target
Others
Related Pathways
Others
Bioactivity
APBC is a novel PD-L1 inhibitor, effectively interrupting the PD-1/PD-L1 interaction by directly binding to PD-L1, presenting the KD and IC50 values at low-micromolar level, displaying superior antitumor efficacy in hPD-L1 knock-in B16F10-bearing mouse model without the induction of observable liver toxicity.
Smiles
N(C(=O)C1=CC=C(C=C1)C2=CC=CC=C2)C3=C(C(N)=O)C=CC=C3
Molecular Formula
C20H16N2O2
Molecular Weight
316.35
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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