Piroxantrone
Product Specifications
CAS Number
91441-23-5
Target
Others, Topoisomerase
Related Pathways
Others, DNA Damage/DNA Repair
Bioactivity
Piroxantrone, also known as CI942; PD111815, is a n anthrapyrazole antineoplastic antibiotic. Piroxantrone intercalates into DNA and interacts with topoisomerase II, thereby inhibiting DNA replication and repair and RNA and protein synthesis. Although less cardiotoxic than doxorubicin, this agent exhibits a narrow spectrum of antineoplastic activity.
Smiles
N(CCCN)C1=C2C=3C(C=4C(C2=O)=C(O)C=CC4O)=NN(CCNCCO)C3C=C1
Molecular Formula
C21H25N5O4
Molecular Weight
411.45
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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