Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

SIN3B Antibody - middle region : HRP (ARP50590_P050-HRP)

Product Specifications

Gene Name

SIN3 transcription regulator homolog B (yeast)

Gene Aliases

KIAA0700

Gene ID

23309

Swiss Prot

O75182

Accession Number

NP_056075

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human SIN3B

Target

SIN3B acts as a transcriptional repressor. It interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Also, it interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. The gene is also able to form a complex with FOXK1 which represses transcription

Partner Proteins

SOX2; HDAC1; HDAC2; UBC; ESR1; AR; TFAP4; TP53; SUMO2; KLF16; MORF4L1; MORF4L2; MRGBP; KDM5A; CIITA; NR1D2; COPS2; SMN1; PBX1; REST; ZBTB4; ARID4A; MYT1; MXI1; SAP25; SMARCE1; SMARCB1; SMARCA4; SMARCA2; CBFA2T3; RNF220; ZBTB16; SETDB1; HDAC9; IKZF4; IKZF1

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 86%; Pig: 100%; Rat: 79%; Zebrafish: 92%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

133kDa

References & Citations

Dhanda, R.S., (er) BMC Mol. Biol. 9, 8 (2008)

Shipping Conditions

Wet Ice

Product Datasheet

Anti-SIN3B (ARP50590_P050-HRP) antibody

Protein Length

1162

NCBI Gene Symbol

SIN3B

NCBI GB Accession Number

SIN3B

Host or Source

Rabbit

Protein Name

Paired amphipathic helix protein Sin3b

Nucleotide Accession Number

NM_015260

Peptide Sequence

LVSDDVCLKVVELYLNEKKRGAAGGNLSSRCVRAARETSYQWKAERCMAD

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

COA5 Human siRNA Oligo Duplex (Locus ID 493753)
SR318636 1 Kit

COA5 Human siRNA Oligo Duplex (Locus ID 493753)

Ask
View Details
Tmem80 Rat shRNA Plasmid (Locus ID 309109)
TR702460 1 Kit

Tmem80 Rat shRNA Plasmid (Locus ID 309109)

Ask
View Details
Anti-Cathepsin C (CTSC) Polyclonal antibody
FY-AB38371-01 1 mL

Anti-Cathepsin C (CTSC) Polyclonal antibody

Ask
View Details
Anti-Cathepsin C (CTSC) Polyclonal antibody
FY-AB38371-02 100 µL

Anti-Cathepsin C (CTSC) Polyclonal antibody

Ask
View Details
Anti-Cathepsin C (CTSC) Polyclonal antibody
FY-AB38371-03 200 µL

Anti-Cathepsin C (CTSC) Polyclonal antibody

Ask
View Details