TC-PTP-IN-1
Product Specifications
CAS Number
1187396-28-6
Target
Phosphatase
Related Pathways
Metabolism
Bioactivity
TC-PTP-IN-1 (compound 8) is a potent inhibitor of TC-PTP, with an IC50 value of 9.2 nM and Ki values of 4.3 nM and 34 nM for TC-PTP and PTP1B, respectively. TC-PTP-IN-1 increases the expression of pSre416 protein. TC-PTP-IN-1 (compound 3) also acts as a TC-PTP ligand for TP1L.
Smiles
[C@@H](CC1=CC=C(C(P(=O)(O)O)(F)F)C=C1)(NC([C@H](CC2=CC=CC=C2)NC(CO[C@@H]3[C@@H](C(C)C)CC[C@H](C)C3)=O)=O)C(N[C@@H](CCCCNC(=O)C4=CC=C(CC)C=C4)C(N)=O)=O
Molecular Formula
C46H62F2N5O9P
Molecular Weight
897.98
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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