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BDNF Rabbit Polyclonal Antibody

Brain-derived neurotrophic factor, also known as BDNF, is a member of the "neurotrophin" family of growth factors, which are related to the canonical "Nerve Growth Factor", NGF. BDNF acts on certain neurons of the central nervous system and the peripheral nervous system, helping to support the survival of existing neurons, and encourage the growth and differentiation of new neurons and synapses. BDNF is actually found in a range of tissue and cell types, not just in the brain. It is also expressed in the retina, the central nervous system, motor neurons, the kidneys, and the prostate. Various studies have shown possible links between BDNF and conditions such as depression, bipolar disorder,schizophrenia, obsessive-compulsive disorder, Alzheimer's disease, Huntington's disease, Rett syndrome, and dementia, as well as anorexia nervosa and bulimia nervosa.

Product Specifications

CAS Number

9007-83-4

Product Name Alternative

Abrineurin antibody ANON2 antibody BDNF antibody BDNF_HUMAN antibody Brain Derived Neurotrophic Factor antibody Brain-derived neurotrophic factor antibody BULN2 antibody MGC34632 antibody Neurotrophin antibody

Abbreviation

BDNF

Swiss Prot

P23560 Human, P21237 Mouse, P23363 Rat

Cellular Locus

Secreted.

Host

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Synthetic peptide within N-terminal human BDNF.

Isotype

IgG

Conjugation

Non-conjugated

Type

Rabbit polyclonal Antibody

Applications

WB, IF-Cell, IHC-P

Positive Control

A172 cell lysates, SHG-44 cell lysates, mouse heart tissue lysates, mouse brain tissue lysates, SHG-44, human lung tissue, mouse lung tissue, mouse testis tissue, mouse heart tissue, rat spinal cord tissue lysates

Concentration

1 mg/mL

Dilution

WB: 1:500 ;IF-Cell: 1:200 ;IHC-P: 1:200

Purity

Immunogen affinity purified.

Form

Liquid

Buffer

1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 28 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Recombinant Antibody

No

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