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RORγ inverse agonist 2

Product Specifications

CAS Number

1242610-59-8

Target

ROR

Related Pathways

Metabolism

Bioactivity

RORγinverse agonist 2 (Compound 15) is a potent inverse agonist of the retinoic acid receptor-related orphan receptor RORγ, with IC50 values of 0.4 μM for Gal4-RORγ and 0.9 μM for full-length RORγ. This compound is useful for researching autoimmune diseases.

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C(O)(=O)[C@]12[C@@]([C@@]3([C@@](C)(CC1)[C@@]4(C)[C@](CC3)([C@]5(C)[C@@](CC4)(C(C)(C)C(=O)/C(=C\C6=CC=CO6)/C5)[H])[H])[H])([C@H](C(C)=C)CC2)[H]

Molecular Formula

C35H48O4

Molecular Weight

532.75

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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