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UCM-05194 ammonium

Product Specifications

Target

LPL Receptor

Related Pathways

GPCR/G Protein

Bioactivity

UCM-05194 (ammonium) is an agonist for the lysophosphatidic acid receptor 1 (LPA1) . It induces calcium mobilization in RH7777 cells expressing LPA1, with an EC50 of 0.24 µM. In B103 rat neuroblastoma cells that overexpress LPA1, UCM-05194 (ammonium) promotes neurite retraction and cell migration. Additionally, it alleviates acetic acid-induced writhing and mechanical hyperalgesia in mice.

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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