JP-163-16
Product Specifications
Target
PROTACs|||Apoptosis|||NF-?B
Related Pathways
Apoptosis|||PROTAC|||NF-?B
Bioactivity
JP-163-16 is a RelA/p65 PROTAC degrader. It selectively reduces the expression of RelA/p65 in cells via a proteasome-dependent mechanism. JP-163-16 induces apoptosis by inhibiting the NF-?B signaling pathway. This compound is applicable for research on RelA/p65-dependent tumors, such as chronic lymphocytic leukemia (CLL) .
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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