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PROTAC HDAC6 degrader 5

Product Specifications

Target

PROTACs, Ligand for E3 Ligase, HDAC

Related Pathways

DNA Damage/DNA Repair, PROTAC, Chromatin/Epigenetic

Bioactivity

PROTACHDAC6 degrader 5 (Compound 5a) is a highly selective PROTAC that targets HDAC6. It effectively degrades HDAC6 in cells with an IC50 of 43 nM. This compound reduces HDAC6 levels through a proteasome-dependent mechanism that relies on CRBN.

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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