Occludin Rabbit Polyclonal Antibody
This gene encodes an integral membrane protein that is required for cytokine-induced regulation of the tight junction paracellular permeability barrier. Mutations in this gene are thought to be a cause of band-like calcification with simplified gyration and polymicrogyria (BLC-PMG), an autosomal recessive neurologic disorder that is also known as pseudo-TORCH syndrome. Alternative splicing results in multiple transcript variants. A related pseudogene is present 1.5 Mb downstream on the q arm of chromosome 5.
Product Specifications
CAS Number
9007-83-4
Product Name Alternative
Abbreviation
OCLN
Swiss Prot
Q16625 Human, Q61146 Mouse, Q6P6T5 Rat
Cellular Locus
Cell membrane.
Host
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Synthetic peptide within human Occludin aa 6-45 conjugated to Keyhole Limpet Haemocyanin (KLH).
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IF-Cell, IHC-P, FC
Positive Control
Mouse kidney tissue lysate, human kidney tissue lysate, Caco-2, human lung tissue, mouse kidney tissue, HepG2.
Concentration
1 mg/mL
Dilution
WB: 1:500-2,000 ;IF-Cell: 1:2,000 ;IHC-P: 1:50-1:200 ;FC: 1:50-1:100
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 59 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No
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