CB-0821
Product Specifications
CAS Number
81430-62-8
Target
HIV Protease, CCR
Related Pathways
GPCR/G Protein, Proteases/Proteasome, Immunology/Inflammation, Microbiology/Virology
Bioactivity
CB-0821 is a high-affinity CCR5 inhibitor with a Ki of 0.04 nM. It effectively binds to the hydrophobic pocket of the CCR5 protein, hindering the interaction between viral proteins and CCR5, thereby blocking virus entry. CB-0821 holds potential for anti-HIV research.
Smiles
N1=C2N=C(C=C(C=3C=CC=CC3)N2N=C1CC=4N=C5N=C(C=C(C=6C=CC=CC6)N5N4)C=7C=CC=CC7)C=8C=CC=CC8
Molecular Formula
C35H24N8
Molecular Weight
556.62
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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