LNK (SH2B3) Mouse Monoclonal Antibody [Clone ID: LBI2C9]
Product Specifications
Background
This gene encodes a member of the SH2B adaptor family of proteins, which are involved in a range of signaling activities by growth factor and cytokine receptors. The encoded protein is a key negative regulator of cytokine signaling and plays a critical role in hematopoiesis. Mutations in this gene have been associated with susceptibility to celiac disease type 13 and susceptibility to insulin-dependent diabetes mellitus.
Synonyms
IDDM20; LNK
Gene Name
Homo sapiens SH2B adaptor protein 3 (SH2B3), transcript variant 1, mRNA.
Gene ID
10019
UniProt
Q9UQQ2
Conjugation
Unconjugated
Related Pathways
Neurotrophin signaling pathway
Field of Research
Neurotrophin signaling pathway
Dilution
WB 1:500, IF 1:100, FLOW 1:100
Form
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Buffer
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Storage Conditions
Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
SH2B3
Overview
Carrier-free (BSA/glycerol-free) SH2B3 mouse monoclonal antibody, clone LBI2C9
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=10019
Uniprot URL
https://www.uniprot.org/uniprot/Q9UQQ2
Curated Selection
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