JNN-5

Product Specifications

Target

JAK

Related Pathways

JAK/STAT signaling|||Angiogenesis|||Stem Cells|||Chromatin/Epigenetic|||Tyrosine Kinase/Adaptors

Bioactivity

JNN-5 is an effective JAK2 selective inhibitor with an IC50 of 0.41 nM. It demonstrates strong antiproliferative activity in TNBC cell lines [MDA-MB-468, MDA-MB-213, HCC70, MDA-MB-157].

Smiles

CC1=C(C2=CN(C(C)C)N=C2)N=C(NC3=CC(CCN(C(/C=C/C(C4=CC=C(Cl)C=C4)=O)=O)C5)=C5C=C3)N=C1

Molecular Formula

C30H29ClN6O2

Molecular Weight

541.04

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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