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ALK5-IN-28

Product Specifications

CAS Number

2785430-84-2

Target

Others|||TGF-beta/Smad

Related Pathways

Stem Cells|||Others

Bioactivity

ALK5-IN-28 is a selective inhibitor of ALK-5 with an IC50 ? 10 nM that inhibits TGF-?-induced SMAD signalling.ALK5-IN-28 has the potential to inhibit tumour growth in vivo.ALK5-IN-28 can be used to study proliferative diseases (e.g. cancer, fibrotic diseases, systemic sclerosis) .

Smiles

N(C=1C2=C(C(C)=CC=C2)N=NC1)C3=NC(NC4=CC=C(CC5CCNCC5)C=C4)=NC=C3

Molecular Formula

C25H27N7

Molecular Weight

425.53

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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