ABZI
Product Specifications
CAS Number
2248444-14-4
Target
STING
Related Pathways
Immunology/Inflammation
Bioactivity
(S) -2- (1-Ethyl-3-methyl-1H-pyrazole-5-carboxamido) -1- (2-hydroxy-2-phenylethyl) -1H-benzo[d]imidazole-5-carboxamide (compound 4) is a STING agonist containing the crucial amide benzimidazole (ABZI) component. It consistently inhibits the binding of 3 H-cGAMP to STING, with an apparent inhibition constant (IC50) of 14 μM. This compound is applicable in tumor research.
Smiles
C([C@@H](O)C1=CC=CC=C1)N2C=3C(N=C2NC(=O)C=4N(CC)N=C(C)C4)=CC(C(N)=O)=CC3
Molecular Formula
C23H24N6O3
Molecular Weight
432.48
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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