SOF-436

Product Specifications

CAS Number

2224491-20-5

Target

Ras

Related Pathways

GPCR/G Protein|||MAPK

Bioactivity

SOF-436 is a KRAS inhibitor that can suppress SOS1-mediated KRAS nucleotide exchange (IC50 = 60 ?M) and inhibit the interaction between KRAS and the effector protein RAF. SOF-436 is applicable to cancer research.

Smiles

O=S(=O)(F)C1=CC=CC(=C1)S(=O)(=O)NC2=CC=C(C(F)=C2)C3CC3

Molecular Formula

C15H13F2NO4S2

Molecular Weight

373.395

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

79344 96 Reactions

FTO Chemiluminescent Assay Kit

Ask

View Details

GWB-D7F8E9 0.1 mg

TFG Over-expression Lysate Product

Ask

View Details

TA365239 100 µL

Caspase 5 (CASP5) Rabbit Polyclonal Antibody

Ask

View Details

BS21913-01 100 µL

Rabbit Anti-Human IgG+IgM+IgA - AF660

Ask

View Details

BS21913-02 500 µL

Rabbit Anti-Human IgG+IgM+IgA - AF660

Ask

View Details

NBP2-41279AF405 0.1 mL

Rabbit Polyclonal Avian Influenza A H7N9 Neuraminidase Antibody [Alexa Fluor 405]

Ask

View Details