LSD1-IN-42
Product Specifications
Target
Histone Demethylase|||PD-1/PD-L1
Related Pathways
Chromatin/Epigenetic|||Apoptosis|||Immunology/Inflammation|||Cell Cycle/Checkpoint
Bioactivity
LSD1-IN-42 (Compound 7ae) is an orally active LSD1 inhibitor that significantly suppresses LSD1 activity (IC50 = 0.08 ?M) . It reduces PD-L1 expression and enhances the tumor-killing effect of T cells. LSD1-IN-42 demonstrates notable anti-gastric cancer activity by inhibiting tumor cell invasion and migration.
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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