Recombinant QSOX1 Monoclonal Antibody
Product Specifications
Background
QSOX1 belongs to the family of FAD-dependent sulfhydryl oxidases and is an atypical disulfide catalyst. QSOX1 is mainly located in the Golgi apparatus and endoplasmic reticulum (ER) in human embryonic fibroblasts, and it cooperates with protein disulfide isomerase (PDI) to help fold new-born proteins in the cell. QSOX1 is mainly expressed in the heart, placenta, lung, liver, skeletal muscle, and pancreas, and is very weakly expressed in the brain and kidneys. Studies have found that the increase of QSOX1 expression in tumor cells enables tumor cells to actively circumvent the mechanism of apoptosis mediated by reactive oxygen species.
Abbreviation
QSOX1
UniProt
O00391
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant human QSOX1 fragment
Target
UNQ; PRO; QSOX; QSCN; QSOX1; Q6; QSCN6; UNQ2520; PRO6013; quiescin sulfhydryl oxidase 1
Clonality
Monoclonal,Recombinant
Clone
A348
Conjugation
Unconjugated
Applications
WB; FCM; IP
Field of Research
Cell Biology
Purification
Protein A purified
Concentration
1 mg/mL
Dilution
WB 1:500-1:1000; FCM 1:100; IP 1:25-1:50
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
83 kDa
Observed Molecular Weight
67 kDa
Isotype
IgG, κ
Available Sizes
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