What is the catalog number for COX-2-IN-51?

The catalog number for COX-2-IN-51 is T204857.

What sizes are available for COX-2-IN-51?

COX-2-IN-51 is available in the following size(s): 10 mg, 50 mg.

How many pack sizes does COX-2-IN-51 come in?

COX-2-IN-51 is available in 2 different pack sizes.

Is COX-2-IN-51 in stock?

COX-2-IN-51 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures COX-2-IN-51?

COX-2-IN-51 is manufactured by Molfinity.

What is the estimated delivery time for COX-2-IN-51?

Estimated delivery time for COX-2-IN-51 is approximately 10 business day(s), depending on your location.

COX-2-IN-51

Product Specifications

CAS Number

3064260-49-4

Target

COX, NF-κB

Related Pathways

NF-κB, Neuroscience, Immunology/Inflammation

Bioactivity

COX-2-IN-51 (E25) is a potent COX-2 inhibitor with an IC50 of 70.7 nM. It significantly suppresses LPS-induced release of NO and PGE2, the expression of COX-2 and iNOS, and the activation of the NF-κB pathway. Displaying anti-inflammatory and analgesic effects in various mouse models through NF-κB pathway inhibition, COX-2-IN-51 has lower gastrointestinal side effects compared to Indomethacin.