T9 peptide

T9 peptide (SKTFNTHPQSTP) is a muscle-targeting peptide that tightly binds to C2C12 myoblasts. When combined with oligonucleotides, T9 peptide enhances specificity towards the heart and quadriceps without similarly targeting the kidney, liver, or diaphragm.

C([C@H](CC1=CN=CN1)NC([C@@H](NC([C@@H](NC([C@H](CC2=CC=CC=C2)NC([C@@H](NC([C@@H](NC([C@H](CO)N)=O)CCCCN)=O)[C@@H](C)O)=O)=O)CC(N)=O)=O)[C@@H](C)O)=O)(=O)N3[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(=O)N4[C@H](C(O)=O)CCC4)[C@@H](C)O)=O)CO)=O)CCC(N)=O)=O)CCC3