HPK1-IN-55
Product Specifications
CAS Number
3048537-58-9
Target
MAPK
Related Pathways
MAPK
Bioactivity
HPK1-IN-55 (compound 19) is a selective and orally active inhibitor of hematopoietic progenitor kinase 1 (HPK1) with an IC50 of less than 0.51 nM. It exhibits exceptional kinase selectivity, being over 637 times more selective for HPK1 compared to GCK kinase and over 1022 times compared to LCK. HPK1-IN-55 possesses anti-cancer properties.
Smiles
O=C(N)C1=NC(=C(OC)C=C1NC=2N=C3C(=CC2)C4(N(C)C3)CCN(CC4)C5COC5)C6=CC=CC7=C6N=CN7C
Molecular Formula
C30H34N8O3
Molecular Weight
554.643
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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