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Thonzylamine

Thonzylamine is an orally active H1 histamine receptor antagonist with good antihistaminic and antianaphylactic properties. Thonzylamine can be used for the research of hypersensitivity diseases, nasal congestion, allergic conjunctivitis and other allergic diseases[1][2].

Product Specifications

CAS Number

[91-85-0]

Product Name Alternative

Neohetramine

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Histamine Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/thonzylamine.html

Purity

98.03

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CN(C)CCN(CC1=CC=C(OC)C=C1)C2=NC=CC=N2

Molecular Formula

C16H22N4O

Molecular Weight

286.37

Precautions

H302, H315, H319, H335

References & Citations

[1]AARON TH, et, al. Neohetramine and thephorin; two new antihistaminic drugs. Can Med Assoc J. 1948 Nov; 59 (5) : 438-41.|[2]Zhou S, et, al. Design, synthesis and biological activity of a novel ethylenediamine derivatives as H 1 receptor antagonists. Bioorg Med Chem. 2019 Dec 15; 27 (24) : 115127.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

Launched

Isoform

H1 Receptor

Available Sizes

Curated Selection

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