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Thrombin inhibitor 13

Product Specifications

Target

Thrombin

Related Pathways

Proteases/Proteasome

Bioactivity

Thrombin inhibitor 13 (Compound 13a) acts as a covalent reversible inhibitor of thrombin (thrombin, FIIa) with an IC50 of 0.7 nM. This compound prolongs activated partial thromboplastin time (aPTT) and prothrombin time (PT), demonstrating both antithrombotic and anticoagulant properties.

Smiles

CC(C)(C)C(=O)N1C(=NC(=N1)C2=NC=CN=C2)NCC3=CC=C(S3)Cl

Molecular Formula

C16H17ClN6OS

Molecular Weight

376.864

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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