CBR-470-1
CBR-470-1 is a potent inhibitor of glycolytic phosphoglycerate kinase 1 (PGK1) that activates NRF2 by increasing methylglyoxal levels. CBR-470-1 is a non-covalent Nrf2 activator with neuroprotective activity that protects SH-SY5Y neuronal cells from MPP+-induced cytotoxicity by activating the Keap1-Nrf2 cascade. cytotoxicity induced by MPP+.
Product Specifications
CAS Number
2416095-06-0
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
365.9
Molecular Formula
C14H20ClNO4S2
Notes
Research use only, not for human use.
Receptor
Nrf2
Available Sizes
Curated Selection
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