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Sesaminol

Product Specifications

CAS Number

74061-79-3

Target

Nrf2|||Reactive Oxygen Species

Related Pathways

Metabolism|||NF-?B|||Immunology/Inflammation

Bioactivity

Sesaminol is an orally active activator of the Nrf2-ARE signaling pathway, promoting the nuclear translocation of Nrf2 and boosting the expression of NQO1 to enhance cellular defense against oxidative stress. It inhibits 6-OHDA-induced ROS production and apoptosis in SH-SY5Y cells. Sesaminol also provides neuroprotective effects against Rotenone-induced Parkinson's disease.

Smiles

OC1=C([C@@H]2[C@@]3([C@@]([C@H](OC3)C=4C=C5C(=CC4)OCO5)(CO2)[H])[H])C=C6C(=C1)OCO6

Molecular Formula

C20H18O7

Molecular Weight

370.35

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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