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Adhibin

Product Specifications

Target

Myosin

Related Pathways

Cytoskeletal Signaling

Bioactivity

Adhibin is an allosteric inhibitor of RhoGAP class IX myosin (RhoGAP class IXmyosin), effectively inhibiting Myo9 ATPase in both mammals and invertebrates with an IC50 of 2.5 μM and 2.6 μM, respectively. It binds to ATPase, disrupting myosin's motor functions, blocking RhoGTPase-related signaling pathways, and affecting cellular migration, adhesion, and division. Adhibin is applicable for research in cancer metastasis.

Molecular Formula

C13H9Br2NO

Molecular Weight

355.02

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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