SJ46411-Br
Product Specifications
Target
Ligand for E3 Ligase
Related Pathways
PROTAC
Bioactivity
SJ46411-Br is an orally effective CK1α molecular glue (Molecular Glue) degrader. It binds with CRL2^KLHDC2 to facilitate the formation of a cooperative homoselective ternary complex. Furthermore, SJ46411-Br is coupled with the BET ligand JQ1 through a PROTAC linker, enabling the synthesis of corresponding PROTACs.
Molecular Formula
C17H13BrN2O3S
Molecular Weight
405.27
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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