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Menin-MLL inhibitor 34

Product Specifications

Target

Epigenetic Reader Domain

Related Pathways

Chromatin/Epigenetic

Bioactivity

Menin-MLL inhibitor 34 (Compound 37) is a selective and potent inhibitor of Menin-MLL, exhibiting an IC50 of 18.21 nM against Menin. This compound effectively reduces Menin protein levels and downregulates MEN1 transcription, demonstrating sustained anti-leukemia effects.

Smiles

O=C1C2=C(C=C(N=C2N(C(=O)N1C)C)N3CCN(C)CC3)NCC(=O)NC=4C=CC=C(Cl)C4

Molecular Formula

C40H54FN9O4S

Molecular Weight

775.98

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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