PROTAC SMARCA2/4-degrader-34
Product Specifications
Target
Epigenetic Reader Domain, PROTACs
Related Pathways
Chromatin/Epigenetic, PROTAC
Bioactivity
PROTAC SMARCA2/4-degrader-34 (compound 38) serves as an effective degrader of both SMARCA2 and SMARCA4. It demonstrates binding affinity to PXR with a DC50 value of 85.1 nM and reduces the protein expression of 3xFLAG-PXR.
Smiles
O([C@H](CCNC)C1=CC=CS1)C=2C3=C(C=CC2)C=CC=C3
Molecular Formula
C58H78N8O13S
Molecular Weight
1127.35
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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