PROTAC 20S proteasome subunit β5 degrader 2
Product Specifications
Target
PROTACs, Proteasome
Related Pathways
Ubiquitination, Proteases/Proteasome, PROTAC
Bioactivity
PROTAC 20S proteasome subunit β5 degrader 2 is a PROTAC degrader targeting the 20S proteasome subunit β5 (20Sproteasomesubunit β5), with a DC50 of 0.16 μM. It inhibits the proliferation of FaDu cancer cells, showcasing an IC50 of 0.23 μM. Additionally, PROTAC20Sproteasomesubunit β5 degrader 2 demonstrates antitumor activity in a mouse model.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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