Monoclonal Anti-AFP (Capture Ab)
Product Specifications
Background
Alpha-fetoprotein (AFP, α-fetoprotein; also sometimes called alpha-1-fetoprotein, alpha-fetoglobulin, or alpha fetal protein) is a protein that in humans is encoded by the AFP gene. The AFP gene is located on the q arm of chromosome 4 (4q25) . Biological response evaluation by the measurement of serial AFP levels is a useful predictor of overall survival and intrahepatic remote recurrence after RFA. Therefore, an initial AFP response may aid in determining the need of closer follow-up as a therapeutic response indicator of RFA.
Host
Mouse
Reactivity
Human
Immunogen
Recombinant Alpha fetal protein (AFP) protein.
Capture Antibody
Capture Ab:AFPmAb (clone # A1) ; Detection Ab:AFPmAb (clone # C3)
Clone
A1
Applications
ELISA; Chemilumineseent immunoassay, CLIA
Purity
>95% by HPLC & SDS-PAGE
Form
Liquid
Buffer
Protein A or G purified and supplied in0.9% NaClwithout preservative.
References & Citations
1. Yu SJ, Kwon JH, Kim W, Yoon JH, Lee JM, Lee JY, Cho EJ, Lee JH, Kim HY, Jung YJ, Kim YJ.Initial Alpha-Fetoprotein Response Predicts Prognosis in Hepatitis B-related Solitary HCC Patients After Radiofrequency Ablation. J Clin Gastroenterol. 2017 Aug 8.
Storage Conditions
Aliquot and store at -20°C for long term (at least one year). Avoid repeated freeze and thaw cycles.
Isotype
IgG1
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