What is the catalog number for Recombinant mouse RANK/TNFRSF11A protein?

The catalog number for Recombinant mouse RANK/TNFRSF11A protein is ATGP4155-020.

What sizes are available for Recombinant mouse RANK/TNFRSF11A protein?

Recombinant mouse RANK/TNFRSF11A protein is available in the following size(s): 20 µg.

Is Recombinant mouse RANK/TNFRSF11A protein in stock?

Recombinant mouse RANK/TNFRSF11A protein is currently made to order / not held in immediate stock. Contact us for lead time.

Recombinant mouse RANK/TNFRSF11A protein

RANK, as known as Tumor necrosis factor receptor superfamily member 11A (TNFRSF11A) is a member of the tumor necrosis factor receptor (TNFR) molecular sub-family. It is the receptor for RANK-Ligand (RANKL) and part of the RANK/RANKL/OPG signaling pathway that regulates osteoclast differentiation and activation. It is associated with bone remodeling and repair, activation of NF-kappa B and c-jun N-terminal kinase, enhancement of T cell growth and dendritic cell function, immune cell function, lymph node development, thermal regulation, and mammary gland development. It is able to block TRANCE induced biological activity. Recombinant mouse RANK, fused to hlgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Product Specifications

Specifications

Mouse RANKL/TNFSF11 (CAT# ATGP3915) is coated at 1 µg/mL (100 ul/well) can bind Mouse RANK/TNFRSF11A. The ED50 range ≤ 200 ng/mL.

Product Name Alternative

TNF receptor superfamily member 11a, Tumor necrosis factor receptor superfamily member 11A, Osteoclast differentiation factor receptor, Receptor activator of NF-KB, Familial expansile osteolysis, TRANCE receptor, RANK, CD265, FEO, ODFR, TRANCE-R, TNR11

Expression System

Baculovirus

Antigen Species

Mouse

Tag

HIgG-His-Tag

Applications

SDS-PAGE, Bioactivity

Concentration

1 mg/mL (determined by absorbance at 280 nm)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 90% by SDS-PAGE

Bioactivity

Measured by its binding ability in a functional ELISA with Mouse RANKL/TNFSF11 (CAT# ATGP3915) . The ED50 range ≤ 200 ng/mL.

Molecular Weight

47.5 kDa (426aa)

Additionnal Information

ATGP4155-10 µg, ATGP4155-20 µg, ATGP4155-50 µg, ATGP4155-100 µg, ATGP4155-250 µg, ATGP4155-500 µg, ATGP4155-1 mg, ATGP4155-010, ATGP4155-020, ATGP4155-050, ATGP4155-100, ATGP4155-250, ATGP4155-500, ATGP4155-01M, ATGP3939-10 µg, ATGP3939-20 µg, ATGP3939-50 µg, ATGP3939-100 µg, ATGP3939-250 µg, ATGP3939-500 µg, ATGP3939-1 mg, ATGP3939-010, ATGP3939-020, ATGP3939-050, ATGP3939-100, ATGP3939-250, ATGP3939-500, ATGP3939-01M

References & Citations

Anderson, D.M. et al. (1997) Nature 390, 175-179.; ; Nakagawa, N. et al. (1998) Biochem. Biophys. Res. Commun. 245:395-400.; ; Bharat B. Aggarwal. (2003) Nature 3, 745-756.;

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Scientific Category

Immunology, Hormones & Cytokines

NCBI Accession Number

NP_033425.3

Uniprot Accession Number

O35305

Species

Mouse

N Terminal Sequence

Ala

AA Sequence

VTPPCTQ ERHYEHLGRC CSRCEPGKYL SSKCTPTSDS VCLPCGPDEY LDTWNEEDKC LLHKVCDAGK ALVAVDPGNH TAPRRCACTA GYHWNSDCEC CRRNTECAPG FGAQHPLQLN KDTVCTPCLL GFFSDVFSST DKCKPWTNCT LLGKLEAHQG TTESDVVCSS SMTLRRPPKE AQAYLPS