What is the catalog number for Recombinant mouse CD39L2/ENTPD6 Protein?

The catalog number for Recombinant mouse CD39L2/ENTPD6 Protein is ATGP3984-020.

What sizes are available for Recombinant mouse CD39L2/ENTPD6 Protein?

Recombinant mouse CD39L2/ENTPD6 Protein is available in the following size(s): 20 µg.

Is Recombinant mouse CD39L2/ENTPD6 Protein in stock?

Recombinant mouse CD39L2/ENTPD6 Protein is currently made to order / not held in immediate stock. Contact us for lead time.

Recombinant mouse CD39L2/ENTPD6 Protein

CD39L2, also known as ENTPD6, is a nucleoside phosphohydrolase of the CD39 family of enzymes that is present on the surface of cells. It is soluble monomeric enzyme, making it more amenable to thorough structural and fuctional analysis than the membrane-bound forms. Soluble CD39L2 preferentially exhibits nucleoside diphosphatase activity, which is depedent on the presence of divalent cations. It is expressed at its highest levels in cardiac muscle and in heart capillary endothelial cells. Also, it plays a role in the regulation and recruitment of platelet activation in heart. Recombinant mouse CD39L2, fused to His-tag at C-terminus, was expressed in HEK293 cell and purified by using conventional chromatography techniques.

Product Specifications

Specifications

Specific activity is > 80,000 pmol/min/ug, and is defined as the amount of enzyme that hydrolyze GDP per minute at pH 7.5 at 25C.

Product Name Alternative

Ectonucleoside triphosphate diphosphohydrolase 6 isoform1, 2700026H11Rik, Cd39l, Cd39l2, dJ738P15.3, NTPDa, NTPDase-6, Entpd6

Expression System

HEK293

Antigen Species

Mouse

Tag

His-Tag

Applications

SDS-PAGE, Enzyme Activity

Concentration

0.25 mg/mL (determined by Absorbance at 280 nm)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 95% by SDS - PAGE

Bioactivity

Specific activity is > 80,000 pmol/min/ug, and is defined as the amount of enzyme that hydrolyze GDP per minute at pH 7.5 at 25C.

Molecular Weight

47.3kDa (433aa)

Additionnal Information

, ATGP3984-10 µg, ATGP3984-20 µg, ATGP3984-50 µg, ATGP3984-100 µg, ATGP3984-250 µg, ATGP3984-500 µg, ATGP3984-1 mg, ATGP3984-10, ATGP3984-20, ATGP3984-50, ATGP3984-100, ATGP3984-250, ATGP3984-500, ATGP3984-1

References & Citations

Yeung G., et al, (2000) Biochemistry. 39:12916-12923.; ; Hicks-Berger CA, et al, (2000) J Biol Chem. 275:34041-34045.; ; Ivanenkov VV, et al, (2003) Biochemistry. 42:11726-11735.;

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid. In Phosphate-Buffered Saline (pH 7.4) containing 20% glycerol

Scientific Category

Signal Transduction, Metabolism

NCBI Accession Number

NP_742115.2

Uniprot Accession Number

Q3U0P5

Species

Mouse

N Terminal Sequence

Asp

AA Sequence

KWHRAS AAQAFFTIAG AASGARWTQQ AFSSPGSAAR GHEVFYGIMF DAGSTGTRIH VFQFARPPGE TPTLTHETFK ALKPGLSAYA DDVEKSAQGI QELLNVAKQH IPYDFWKATP LVLKATAGLR LLPGEKAQKL LQKVKEVFKA SPFLVGDDCV SIMNGTDEGV SAWITVNFLT GSLKTPGSSS VGMLDLGGGS TQITFLPRVE GTLQASPPGH LTALQMFNRT YKLYSYSYLG LGLMSARLAI LGGVEGKPAE NDKELVSPCL SPRFRGEWEH AEVTYRISGQ KAVGLYELCA SRVSEVLRNK VHRTEEAQHV DFYAFSYYYD LAASFGLIDA EKGGSLVVGD FEIAAKYVCR TLETQPPSSP FACMDLTYIS LLLHEFGFPG DKVLKLARKI DNVETSWALG AIFHYIDSLK RQKVPAL