Recombinant human LOX-1/OLR1 protein
OLR1, as known as oxidized low-density lipoprotein receptor 1, is a type 2 transmembrane receptor belonging to the C-type lectin family. It belongs to the functionally defined scavenger receptor (SR) superfamily. This protein is the first member of the class E scavenger receptor subfamily. Also, this protein may play a role in the progression of vulnerable carotid plaque and might regulate vulnerable plaque formation in cooperation with MMPs and TIMP2. Recombinant human OLR1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Oxidized low-density lipoprotein receptor 1 isoform 1, OLR1, CLEC8A, LOX1, hLOX-1, LOXIN, SCARE1, SLOX1
Expression System
Baculovirus
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by absorbance at 280 nm)
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Purity
> 95% by SDS-PAGE
Molecular Weight
25.8 kDa (225aa)
Additionnal Information
References & Citations
Higuma T., et al, (2015) Circ. J. 79:641-648.; ; Tejedor JR., et al, (2015) RNA. 21:1187-1202.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Scientific Category
Cardiovascular
NCBI Accession Number
NP_002534
Uniprot Accession Number
P78380
Species
Human
N Terminal Sequence
Ala
AA Sequence
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