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Recombinant mouse CD107b/LAMP2 protein

Lamp2, also known as lysosome-associated membrane glycoprotein 2, is a major component of lysosomal membranes. It is clinically characterized by cardiomyopathy, myopathy, and variable mental retardation. Up-regulated Lamp2 at the plasma membrane serves as an indicator of cell activation of CD8+ T cells, mast cells, monocytes, and platelets. Recombinant mouse Lamp2, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Lysosome-associated membrane glycoprotein 2, CD107 antigen-like family member B, CD107b, Lysosomal membrane glycoprotein type B, LGP-B, Lamp-2

Expression System

Baculovirus

Antigen Species

Mouse

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by absorbance at 280 nm)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 95% by SDS-PAGE

Molecular Weight

40.2 kDa (362aa)

Additionnal Information

Lamp2, Lysosome-associated membrane glycoprotein 2, Lamp2, CD107b, Lamp II, Lamp-2, Lamp-2a, Lamp-2b, Lamp-2c, LGP-B, Mac3, ATGP3373-10 µg, ATGP3373-20 µg, ATGP3373-50 µg, ATGP3373-100 µg, ATGP3373-250 µg, ATGP3373-500 µg, ATGP3373-1 mg, ATGP3373-10, ATGP3373-20, ATGP3373-50, ATGP3373-100, ATGP3373-250, ATGP3373-500, ATGP3373-1

References & Citations

Eskelinen EL., et al. (2003) Trends Cell Biol. 13:137-145.; ; Bertini E., et al. (2005) Neuropediatrics. 36:309-313.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Scientific Category

Tags & Cell Markers

NCBI Accession Number

NP_001017959

Uniprot Accession Number

P17047

Species

Mouse

N Terminal Sequence

Leu26

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