Recombinant human CAMK2N2 protein
Calcium/calmodulin-dependent protein kinase II, also known as CAMK2N2, is potent and specific cellular inhibitor of CaM-kinase II (CAMK2) . This protein may play an important role in the regulation of cell growth when overexpressed in colon adenocarcinoma LoVo cells. Recombinant human CAMK2N2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Calcium/calmodulin-dependent protein kinase II, CAM-KIIN, CAMKIIN
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 95% by SDS-PAGE
Molecular Weight
11.0 kDa (102aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Zhang J., et al. (2001) Biochem. Biophys. Res. Commun. 285:229-234; ; Ma S., et al. (2009) J. Biol. Chem. 284:24773-24782
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT
Scientific Category
Neuroscience
NCBI Accession Number
NP_150284
Uniprot Accession Number
Q96S95
Species
Human
AA Sequence
MSEILPY SEDKMGRFGA DPEGSDLSFS CRLQDTNSFF AGNQAKRPPK LGQIGRAKRV VIEDDRIDDV LKGMGEKPPS GV
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