Recombinant human MBIP protein

MBIP inhibits the MAP3K12 activity to induce the activation of the JNK/SAPK pathway. This protein is a component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. Recombinant human MBIP protein, fused to His-tag at N-terminus, was expressed in E. coli

Product Specifications

Product Name Alternative

MAP3K12-binding inhibitory protein 1 isoform 1, MAP3K12 binding inhibitory protein 1

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE, Denatured

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 85% by SDS-PAGE

Molecular Weight

41.7 kDa (367aa)

Additionnal Information

MBIP, MAP3K12-binding inhibitory protein 1 isoform 1, MAP3K12 binding inhibitory protein 1, ATGP2464-10 µg, ATGP2464-20 µg, ATGP2464-50 µg, ATGP2464-100 µg, ATGP2464-250 µg, ATGP2464-500 µg, ATGP2464-1 mg, ATGP2464-10, ATGP2464-20, ATGP2464-50, ATGP2464-100, ATGP2464-250, ATGP2464-500, ATGP2464-1

References & Citations

Guelman S., Kozuka K. et al. (2009) . Mol. Cell. Biol. 29:1176-1188

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing , 10% glycerol, 0.4M urea

Scientific Category

Signal Transduction

NCBI Accession Number

NP_057670

Uniprot Accession Number

Q9NS73

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MGSMAAATEL NRPSSGDRNL ERRCRPNLSR EVLYEIFRSL HTLVGQLDLR DDVVKITIDW NKLQSLSAFQ PALLFSALEQ HILYLQPFLA KLQSPIKEEN TTAVEEIGRT EMGNKNEVND KFSIGDLQEE EKHKESDLRD VKKTQIHFDP EVVQIKAGKA EIDRRISAFI ERKQAEINEN NVREFCNVID CNQENSCART DAIFTPYPGF KSHVKVSRVV NTYGPQTRPE GIPGSGHKPN SMLRDCGNQA VEERLQNIEA HLRLQTGGPV PRDIYQRIKK LEDKILELEG ISPEYFQSVS FSGKRRKVQP PQQNYSLAEL DEKISALKQA LLRKSREAES MATHHLP