Anti-Rhodopsin Antibody

Our Anti-Rhodopsin mouse monoclonal primary antibody detects bovine, human, mouse, pig, and rat Rhodopsin , and is affinity-purified. It is validated for use in IHC-Frozen, WB.

Product Specifications

Background

Photoreceptor required for image-forming vision at low light intensity. Required for photoreceptor cell viability after birth (By similarity) . Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change that activates signaling via G-proteins (PubMed:10926528, PubMed:12044163, PubMed:11972040, PubMed:16908857, PubMed:16586416, PubMed:17060607, PubMed:17449675, PubMed:18818650, PubMed:21389983, PubMed:22198838, PubMed:23579341, PubMed:25205354, PubMed:27458239) . Subsequent receptor phosphorylation mediates displacement of the bound G-protein alpha subunit by the arrestin SAG and terminates signaling (PubMed:1396673, PubMed:15111114) . Ref: uniprot.org

Short Description

Our Anti-Rhodopsin mouse monoclonal primary antibody detects bovine, human, mouse, pig, and rat Rhodopsin, and is affinity-purified. It is validated for use in IHC-Frozen, WB.

UniProt

P02699

Reactivity

Bovine, Human, Mouse, Pig, and Rat

Immunogen

Purified bovine rhodopsin

Target

Rhodopsin

Clonality

Monoclonal

Clone

B630

Conjugation

Unconjugated

Applications

IHC-Frozen, WB

Format

Affinity-purified

Buffer

Lyophilized from PBS buffer pH 7.2-7.6 with 0.1% trehalose, and sodium azide.

Precautions

For research use only.

Shipping Conditions

25°C (ambient)

Storage Conditions

Spin vial briefly before opening. Reconstitute with 100 μL sterile-filtered, ultrapure water to achieve a 1 mg/mL concentration. Centrifuge to remove any insoluble material. Store lyophilized antibody at 2-8°C. After reconstitution divide into aliquots and store at -20°C for long-term storage. Store at 2-8°C short-term (up to 4 weeks) with an appropriate antibacterial agent. Avoid repetitive freeze/thaw cycles.