Recombinant human TBC1D1 protein

TBC1 (tre-2/uSP6, BuB2, cdc16) domain family, member 1, also known as TBC1D1, may act as a GTPase-activating protein for Rab family protein (s) . This protein may play a role in the cell cycle and differentiation of various tissues. This protein is involved in the trafficking and translocation of GLuT4-containing vesicles and insulin-stimulated glucose uptake into cells. Recombinant human TBC1D1 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Product Specifications

Product Name Alternative

TBC1 (tre-2/uSP6 BuB2 cdc16) domain family member 1, TBC1 (tre-2/uSP6, BuB2, cdc16) domain family, member 1, TBC, TBC1

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE, Denatured

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

33.2 kDa (288aa)

Additionnal Information

TBC1D1, TBC1 (tre-2/uSP6 BuB2 cdc16) domain family member 1, TBC1 (tre-2/uSP6, BuB2, cdc16) domain family, member 1, TBC, TBC1, ATGP2412-10 µg, ATGP2412-20 µg, ATGP2412-50 µg, ATGP2412-100 µg, ATGP2412-250 µg, ATGP2412-500 µg, ATGP2412-1 mg, ATGP2412-10, ATGP2412-20, ATGP2412-50, ATGP2412-100, ATGP2412-250, ATGP2412-500, ATGP2412-1

References & Citations

Stone S., et al. (2006) Hum. Mol. Genet. 15:2709-2720; ; Meyre D., et al. (2008) Hum. Mol. Genet. 17:1798-1802;

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 0.4M urea

Scientific Category

Signal Transduction

NCBI Accession Number

NP_001240842

Uniprot Accession Number

Q8NC59

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MGSMSEEEAF KMLKFLMFDM GLRKQYRPDM IILQIQMYQL SRLLHDYHRD LYNHLEEHEI GPSLYAAPWF LTMFASQFPL GFVARVFDMI FLQGTEVIFK VALSLLGSHK PLILQHENLE TIVDFIKSTL PNLGLVQMEK TINQVFEMDI AKQLQAYEVE YHVLQEELID SSPLSDNQRM DKLEKTNSSL RKQNLDLLEQ LQVANGRIQS LEATIEKLLS SESKLKQAML TLELERSALL QTVEELRRRS AEPSDREPEC TQPEPTGD