DCM–ONOO

DCM-ONOO is a near-infrared two-photon fluorescence probe specifically designed for real-time monitoring of the dynamic fluctuations of peroxynitrite (ONOO⁻) in epilepsy models. DCM-ONOO exhibits excellent optical properties, with a single photon excitation (Ex) of 520 nm; a single photon emission (Em) of 685 nm; a two-photon excitation of 820 nm; and a Stokes shift of 165 nm. When DCM-ONOO is combined with ONOO⁻, it shifts from 460 nm to 512 nm, and only generates a significant fluorescence response to ONOO⁻. DCM-ONOO has been successfully applied to rat epilepsy models[1].

Product Specifications

CAS Number

[2759816-87-8]

UNSPSC

12352005

Target

Fluorescent Dye

Related Pathways

Others

Field of Research

Neurological Disease

Smiles

N#C/C(C#N)=C1C=C(OC2=CC=CC=C2\1)/C=C/C3=CC=C(C=C3)NP(C4=CC=CC=C4)(C5=CC=CC=C5)=O

Molecular Formula

C32H22N3O2P

Molecular Weight

511.51

References & Citations

[1]Luo X, et al. Indication of Dynamic Peroxynitrite Fluctuations in the Rat Epilepsy Model with a Near-Infrared Two-Photon Fluorescent Probe. Anal Chem. 2021 Feb 2;93 (4) :2490-2499.