Recombinant human LPCAT1 protein

Lysophosphatidylcholine acyltransferase 1, also known as LPCAT1, belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. It is a key enzyme for remodeling phospholipids, including phosphatidylcholine. LPCAT1 possesses both acyltransferase and acetyltransferase activities. It mediates the conversion of 1-acyl-sn-glycero-3-phosphocholine (LPC) into phosphatidylcholine (PC) . Recombinant human LPCAT1 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Product Specifications

Product Name Alternative

Lysophosphatidylcholine acyltransferase 1, AYTL2, lpcat, PFAAP3

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE, Denatured

Concentration

0.25 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

53.4 kDa (479aa)

Additionnal Information

LPCAT1, Lysophosphatidylcholine acyltransferase 1, AYTL2, lpcat, PFAAP3, ATGP2012-10 µg, ATGP2012-20 µg, ATGP2012-50 µg, ATGP2012-100 µg, ATGP2012-250 µg, ATGP2012-500 µg, ATGP2012-1 mg, ATGP2012-10, ATGP2012-20, ATGP2012-50, ATGP2012-100, ATGP2012-250, ATGP2012-500, ATGP2012-1

References & Citations

Yamazaki T., et al. (2012) Biol Pharm Bull. 35 (9) :1509-15.; ; Kazachkov M., et al. (2001) Lipids. 43 (10) :895-902.;

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 1M urea, 10% glycerol

Scientific Category

Metabolism

NCBI Accession Number

NP_079106

Uniprot Accession Number

Q8NF37

Species

Human

AA Sequence

SAEKEPE QPPALWRKVV DFLLKAIMRT MWFAGGFHRV AVKGRQALPT EAAILTLAPH SSYFDAIPVT MTMSSIVMKA ESRDIPIWGT LIQYIRPVFV SRSDQDSRRK TVEEIKRRAQ SNGKWPQIMI FPEGTCTNRT CLITFKPGAF IPGAPVQPVV LRYPNKLDTI TWTWQGPGAL EILWLTLCQF HNQVEIEFLP VYSPSEEEKR NPALYASNVR RVMAEALGVS VTDYTFEDCQ LALAEGQLRL PADTCLLEFA RLVRGLGLKP EKLEKDLDRY SERARMKGGE KIGIAEFAAS LEVPVSDLLE DMFSLFDESG SGEVDLRECV VALSVVCRPA RTLDTIQLAF KMYGAQEDGS VGEGDLSCIL KTALGVAELT VTDLFRAIDQ EEKGKITFAD FHRFAEMYPA FAEEYLYPDQ THFESCAETS PAPIPNGFCA DFSPENSDAG RKPVRKKLD