Asciminib (Standard)
Asciminib (Standard) is the analytical standard of Asciminib. This product is intended for research and analytical applications. Asciminib (ABL001) is a potent and selective allosteric BCR-ABL1 inhibitor, which inhibits Ba/F3 cells grown with an IC50 of 0.25 nM[1].
Product Specifications
CAS Number
[1492952-76-7]
Product Name Alternative
ABL001 (Standard)
UNSPSC
12352005
Target
Bcr-Abl; Reference Standards
Type
Reference Standards
Related Pathways
Others; Protein Tyrosine Kinase/RTK
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/asciminib-standard.html
Smiles
O=C(C1=CC(C2=NNC=C2)=C(N3C[C@H](O)CC3)N=C1)NC4=CC=C(OC(F)(Cl)F)C=C4
Molecular Formula
C20H18ClF2N5O3
Molecular Weight
449.84
References & Citations
[1]Wylie AA, et al. The allosteric inhibitor ABL001 enables dual targeting of BCR-ABL1. Nature. 2017 Mar 30;543 (7647) :733-737.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Available Sizes
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