Recombinant human GRP/LGALSL protein

Galectin-related protein, also known as LGALSL, is a 172 amino acid protein that contains one galectin domain. Galectins are a family of soluble b-galactoside-binding animal lectins that modulate cell-to-cell adhesion and cell-to-extracellular matrix (ECM) interactions and also play a role in tumor progression, pre-mRNA splicing and apoptosis. However, LGALSL does not appear to bind carbohydrates or lactose because the critical residues required for binding are not conserved. Recombinant human LGALSL protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Galectin-related protein, GRP, Galectin like protein, HSPC159, Lectin galactoside-binding-like protein

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

21.4 kDa (195aa) confirmed by MALDI-TOF

Additionnal Information

Galectin like protein, Galectin related protein, Galectin-related protein, GRP, HSPC159, Lectin galactoside binding like protein, Lectin galactoside-binding-like protein, MGC33751, MGC71953, ATGP1981-10 µg, ATGP1981-20 µg, ATGP1981-50 µg, ATGP1981-100 µg, ATGP1981-250 µg, ATGP1981-500 µg, ATGP1981-1 mg, ATGP1981-010, ATGP1981-020, ATGP1981-050, ATGP1981-100, ATGP1981-250, ATGP1981-500, ATGP1981-01M

References & Citations

Zhou D., et al. (2008) Proteins. 71:1582-1588; ; Walti M A., et al. (2008) Proteins. 72: 804-808.;

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 20% glycerol, 1mM DTT

Scientific Category

Other

NCBI Accession Number

NP_054900

Uniprot Accession Number

Q3ZCW2

Species

Human

AA Sequence

MAGSVAD SDAVVKLDDG HLNNSLSSPV QADVYFPRLI VPFCGHIKGG MRPGKKVLVM GIVDLNPESF AISLTCGDSE DPPADVAIEL KAVFTDRQLL RNSCISGERG EEQSAIPYFP FIPDQPFRVE ILCEHPRFRV FVDGHQLFDF YHRIQTLSAI DTIKINGDLQ ITKLG