Kasugamycin (hydrochloride)
Kasugamycin (Ksg) hydrochloride hydrate is an antibiotic that binds to 30s and 70s ribosomes but not to the 50s subunit, and has anti-infective activity. Kasugamycin hydrochloride hydrate mimics mRNA nucleotides, disrupts tRNA binding and inhibits canonical translation initiation. Kasugamycin hydrochloride hydrate increases the sensitivity of mycobacteria to Rifampicin (HY-B0272) in vitro and in mouse infection models[1][2][3].
Product Specifications
CAS Number
[19408-46-9]
Product Name Alternative
Ksg (hydrochloride)
UNSPSC
12352005
Hazard Statement
H302, H315, H320, H335
Target
Antibiotic; Bacterial
Type
Natural Products
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/kasugamycin-hydrochloride.html
Purity
99.95
Solubility
H2O : 25 mg/mL (ultrasonic)
Smiles
OC(C(N[C@@H](C[C@@H]1N)[C@@H](C)O[C@]1([H])O[C@@H]2[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)[C@H]2O)=N)=O.[H]Cl
Molecular Formula
C14H26ClN3O9
Molecular Weight
415.82
Precautions
H302, H315, H320, H335
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-B1864A/Kasugamycin-hydrochloride-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-B1864A/Kasugamycin-hydrochloride-SDS-MedChemExpress.pdf
Scientific Category
Natural Products
Clinical Information
Launched
Available Sizes
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