Recombinant human OBFC1 protein
CST complex subunit STN1, also known as OBFC1, is a component of the CST complex, a complex that binds to single-stranded DNA and is required to protect telomeres from DNA degradation. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. In addition to telomere protection, the CST complex has probably a more general role in DNA metabolism at non-telomeric sites. Recombinant human OBFC1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
CST complex subunit STN1, AAF-44, RPA-32, STN1
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by Bradford assay)
Purity
> 85% by SDS-PAGE
Molecular Weight
44.5 kDa (391aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Miyake Y., et al. (2009) Mol. Cell. 36:193-206; ; Wan M., et al. (2009) J. Biol. Chem. 284:26725-26731
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 20% glycerol, 1mM DTT
Scientific Category
Epigenomics (Transcription & Translation)
NCBI Accession Number
NP_079204.1
Uniprot Accession Number
Q9H668
Species
Human
AA Sequence
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
HSPH1 (HSPH1, Heat shock 105kD beta, Heat shock 110kD Protein, Heat shock Protein 105kD, HSP105, HSP110, Heat-shock Protein 105 kd, HSP105A, HSP105B, NY-CO-25, KIAA0201, Antigen NY-CO-25, Heat shock 105kD alpha, Heat shock 105kDa Protein 1) discontinued
![ALK Mouse Monoclonal Antibody [Clone ID: LBI11H4]](https://cdn.genprice.uk/genprice/uk/genprice3.webp)