Cdc7 Rabbit Polyclonal Antibody
Product Specifications
Background
This gene encodes a cell division cycle protein with kinase activity that is critical for the G1/S transition. The yeast homolog is also essential for initiation of DNA replication as cell division occurs. Overexpression of this gene product may be associated with neoplastic transformation for some tumors. Multiple alternatively spliced transcript variants that encode the same protein have been detected. [provided by RefSeq, Aug 2008], alternative products:A number of isoforms may be produced, catalytic activity:ATP + a protein = ADP + a phosphoprotein., cofactor:Magnesium., function:Seems to phosphorylate critical substrates that regulate the G1/S phase transition and/or DNA replication. Can phosphorylates MCM2 and MCM3., similarity:Belongs to the protein kinase superfamily., similarity:Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC7 subfamily., similarity:Contains 1 protein kinase domain., subunit:Forms a complex with either DBF4/DBF4A or DBF4B, leading to the activation of the kinase activity.
Product Name Alternative
CDC7; CDC7L1; Cell division cycle 7-related protein kinase; CDC7-related kinase; HsCdc7; huCdc7
Gene Name
CDC7
Gene ID
8317
Swiss Prot
O00311
Host
Rabbit
Reactivity
Human, Rat, Mouse
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB, IHC, ICC/IF, ELISA
Field of Research
Cell_Cycle_G1S; Cell_Cycle_G2M_DNA
Purification
Affinity purification
Dilution
WB 1:500-1:2000, IHC 1:100-1:300, ICC/IF 1:50-1:200, ELISA 1:5000-1:10000
Form
Liquid
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Modification
Unmodified
Molecular Weight
70kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
Curated Selection
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