Recombinant human TXNL4A protein

Thioredoxin-like 4A, also known as TXNL4A, belongs to the Dim protein family. TXNL4A is a 142 amino acid protein that plays an essential role in pre-mRNA splicing. Due to a failure to express early zygotic transcripts, deletion of the gene encoding TXNL4A in Schizosaccharomyces pombe leads to embryonal lethality during gastrulation. Localized to the nucleus, TXNL4A interacts with hnRNP F, hnRNP H2, Cas-L and PQBP-1 to effect gene expression. Recombinant human TXNL4A protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Thioredoxin-like 4A, DIB1, DIM1, HsT161, TXNL4, u5-15kD

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by Bradford assay)

Purity

> 95% by SDS-PAGE

Molecular Weight

19.3 kDa (166aa) confirmed by MALDI-TOF

Additionnal Information

TXNL4A, Thioredoxin-like 4A, DIB1, DIM1, HsT161, TXNL4, u5-15kD, ATGP1539-10 µg, ATGP1539-20 µg, ATGP1539-50 µg, ATGP1539-100 µg, ATGP1539-250 µg, ATGP1539-500 µg, ATGP1539-1 mg, ATGP1539-10, ATGP1539-20, ATGP1539-50, ATGP1539-100, ATGP1539-250, ATGP1539-500, ATGP1539-1

References & Citations

Zhang Y Z., et al. (1999) Physiol Genomics. 1:109-118.; ; Zhang Y Z., et al. (2000) Gene. 257: 33-43.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 20% glycerol, 1mM DTT

Scientific Category

Epigenomics (Transcription & Translation)

NCBI Accession Number

NP_006692

Uniprot Accession Number

P83876

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MGSHMSYMLP HLHNGWQVDQ AILSEEDRVV VIRFGHDWDP TCMKMDEVLY SIAEKVKNFA VIYLVDITEV PDFNKMYELY DPCTVMFFFR NKHIMIDLGT GNNNKINWAM EDKQEMVDII ETVYRGARKG RGLVVSPKDY STKYRY