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VEGFR-2-IN-32

Product Specifications

UNSPSC Description

VEGFR-2-IN-32 (Comp 3a) is an inhibitor of VEGFR-2 with an IC50 of 8.93 nM. VEGFR-2-IN-32 has cytotoxic activity against PC-3 cells with an IC50 of 1.22 μM. VEGFR-2-IN-32 can be used for anti-prostate cancer research[1].

Target Antigen

VEGFR

Type

Reference compound

Related Pathways

Protein Tyrosine Kinase/RTK

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/vegfr-2-in-32.html

Solubility

10 mM in DMSO

Smiles

O=C1NN=C(/C1=N/NC2=CC=CC=C2)C3=CC=CC=C3

Molecular Weight

264.28

References & Citations

[1]Soliman DH, et.al. Design, synthesis, and docking studies of novel pyrazole-based scaffolds and their evaluation as VEGFR2 inhibitors in the treatment of prostate cancer. RSC Adv. 2023 Jul 10;13(30):20443-20456.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-155610/VEGFR-2-IN-32-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-155610/

Clinical Information

No Development Reported

Curated Selection

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